Acknowledgements
Preface

Chapter 1 Introduction
Abstract
1．1 What is Endemic Disease?
1．2 How to Classify the Endemic Diseases
1．3 Endemic Diseases in China
1．4 Epidemiological Characteristics of the Endemic Diseases
1．5 The History for Endemic Disease Prevention and Control
1．6 Achievements for the Endemic Disease Control in China
1．7 The Strategy for Endemic Disease Control and Prevention in China
1．8 The Experience for Endemic Disease Control and Prevention in China

Chapter 2 Iodine Deficiency Disorders （IDD）
Abstract
2．1 The Main Manifestations and Harms of Iodine Deficiency
2．2 The Story of IDD Discovery
2．3 Distribution of IDD?
2．4 Classifications of IDD Endemic Areas in China
2．5 Prevention Strategies and Measures of IDD?
2．6 IDD Surveillance
2．7 Achievements in IDD Prevention and Control of China

Chapter 3 Endemic Fluorosis
Abstract
3．1 General Introduction to Endemic Fluorosis
3．2 Characteristics of Factors that Influence Endemic Fluorosis
3．3 What Is Metabolic Pathway and Physiological Role of Fluoride in Our Body?
3．4 Which Organs or Systems Are Impaired by Endemic Fluorosis?
3．5 Can Endemic Fluorosis Be Diagnosed Clinically?
3．6 Characterization of the Different Regions of Endemic Fluorosis
3．7 Definition of Regions with Endemic Fluorosis and Different Degrees of Severity
3．8 Prevention and Control of Endemic Fluorosis
3．9 Can Endemic Fluorosis Be Treated?
3．10 History of Control of Endemic Fluorosis in China
3．11 The Achievements of China' s Programs for Prevention and Control of Endemic Fluorosis

Chapter 4 Endemic Arsenic Poisoning
Abstract
4．1 Background of Endemic Arsenic Poisoning in China
4．2 The Classification and Geological Environment of Endemic Arsenicosis Areas
4．3 Epidemiology of Endemic Arsenic Poisoning in China
4．4 Mechanism of arsenicosis
4．5 Clinical Manifestations
4．6 Diagnostic Criteria of Endemic Arsenicosis in China
4．7 Definition and Classification of Endemic Arsenicosis Area
4．8 China' s Approach for Prevention and Control of endemic arsenicosis
4．9 China' s Achievement and Experience

Chapter 5 Kashin-Beck Disease （KBD）
Abstract
5．1 The Discovery of The Disease
5．2 Epidemiology and Disease Characteristics
5．3 Etiology and Epidemic Mechanism
5．4 Clinical Manifestation and Diagnosis
5．5 Prevention and Control of KBD
5．6 The Treatment and Its Unified Evaluation Standard for KBD
5．7 More Experience of Prevention and Control of KBD

Chapter 6 Keshan Disease
Abstract
6．1 The Discovery of KD
6．2 Epidemiology
6．3 Etiology
6．4 Clinical Manifestation and Diagnosis
6．5 Cardiac Histopathology
6．6 Therapies
6．7 Prevention Measures
6．8 Surveillance
6．9 Achievements
6．10 Valuable Experiences in Control and Prevention of KD