Section 1 Principles of Drug Therapy
Chapter 1 Introduction to Pharmacology
The Aim of Pharmacology
The History of Pharmacology
Change of Drug Discovery Strategy
Processes of Drug Discovery
Preclinical Pharmacology Research
(Non-clinical Research)
Clinical Trial
Chapter 2 Pharmacokinetics
Process of Drug in Body
Process for Drug Transport across
Membranes and Drug Transporters
Drug Absorption and Routes of
Administration
Drug Distribution and Binding to Plasma Protein
Drug Metabolism
Drug Elimination
Kinetic Process of Drug in Body
Principles of Pharmacokinetics
Pharmacokinetic Parameters and Basic Calculation Equations
Chapter 3 Pharmacodynamics
Specific Mechanisms of Drug Action
Drug-receptor Interactions
Effects on��Enzymes
Effects on Transporters
Effects on Structural and Functional Proteins
Effects on Genes
Common Note Concerning the Drug
Mechanism
Non-specific Mechanisms of Drug Action
Dose-response Relationships
Dose-response Relationship Curves
Relation between Dose-response
Variation in Drug Responsiveness
Sources of Inter-individual Variation of Drug Response

Section 2 Drugs Affecting the Autonomic Nervous System
Chapter 4 Introduction
Anatomy arid General Functions of
Efferent Nervous System
Autonomic Nervous System
Somatic Motor Nerves
Neurotransmitters in the Efferent Nervous System
Acetylcholine
Norepinephrine
Receptors in the Efferent Nervous System
Cholincceptors
Adrenoceptors
Dopamine Receptors
Drugs Affecting the Autonomic Nervous System
Agonist and Antagonist Actions at Receptors
Interference with Synthesis of the Transmitter
Interference with Degradation of the Transmitter
Interference with Storage and Release of the Transmitter
……
Section 3 Drugs Affecting Central Nerv0us System
Section 4 Cardiovascular Pharmacology
Section 5 Inflammation��Immunomoudlation and Autacoid Pharmacology
Section 6 Endocrine Drugs
Section 7 Drugs Affecting Other Systems
Section 8 Chemotherapeutic Drugs
Index