Contributors. . vii Preface. . ix SECTION I INTRODUCTION TO THE RENAL SYSTEM Cellular and Molecular Biology of the Kidney. Alfred L. George, Jr., Eric G. Neilson Adaptation of the Kidney to Injury. Joseph V. Bonventre SECTION II ALTERATIONS OF RENAL FUNCTION AND ELECTROLYTES Azotemia and Urinary Abnormalities. Julie Lin, Bradley M. Denker Atlas of Urinary Sediments and Renal Biopsies. Agnes B. Fogo, Eric G. Neilson Acidosis and Alkalosis. Thomas D. DuBose, Jr. Fluid and Electrolyte Disturbances. David B. Mount Hypercalcemia and Hypocalcemia. Sundeep Khosla Gout and Other Crystal-Associated Arthropathies. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . H. Ralph Schumacher, Lan X. Chen Nephrolithiasis. Gary C. Curhan SECTION III ACUTE KIDNEY INJURY AND CHRONIC RENAL FAILURE Acute Kidney Injury. Sushrut S. Waikar, Joseph V. Bonventre Chronic Kidney Disease. Joanne M. Bargman, Karl Skorecki Dialysis in the Treatment of Renal Failure. Kathleen D. Liu, Glenn M. Chertow Transplantation in the Treatment of Renal Failure. Jamil Azzi, Edgar L. Milford, Mohamed H. Sayegh, Anil Chandraker Infections in Transplant Recipients. W. Finberg Robert, Joyce Fingeroth SECTION IV GLOMERULAR AND TUBULAR DISORDERS Glomerular Diseases. Julia B. Lewis, Eric G. Neilson Polycystic Kidney Disease and Other Inherited Disorders of Tubule Growth and Development. Jing Zhou, Martin R. Pollak Tubulointerstitial Diseases of the Kidney. Laurence H. Beck, David J. Salant SECTION V RENAL VASCULAR DISEASE Vascular Injury to the Kidney. Nelson Leung, Stephen C. Textor Hypertensive Vascular Disease. Theodore A. Kotchen Renovascular Disease. Stephen C. Textor SECTION VI URINARY TRACT INFECTIONS AND OBSTRUCTION Urinary Tract Infections, Pyelonephritis, and Prostatitis. Kalpana Gupta, Barbara W. Trautner Urinary Tract Obstruction. Julian L. Seifter Bladder and Renal Cell Carcinomas. Howard I. Scher, Jonathan E. Rosenberg, Robert J. Motzer CONTENTS Harrison_ Appendix Laboratory Values of Clinical Importance. . . . . . Alexander Kratz, Michael A. Pesce, Robert C. Basner, Andrew J. Einstein Review and Self-Assessment. . . . . . . . . . . . . . . . . . . . . Charles M. Wiener, Cynthia D. Brown, Brian Houston Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .