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節律與同步-神經科學百科全書-14 版權信息
- ISBN:9787030280763
- 條形碼:9787030280763 ; 978-7-03-028076-3
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節律與同步-神經科學百科全書-14 本書特色
《神經科學百科全書14:節律與同步(導讀版)》是由科學出版社出版的。
節律與同步-神經科學百科全書-14 目錄
節律與同步-神經科學百科全書-14 節選
《神經科學百科全書14:節律與同步(導讀版)》原書篇幅巨大,為所有神經科學百科全書之首。由來自世界各地的2400多位專家撰稿人合力打造,覆蓋了神經科學全部主要領域。每個詞條在收入書中之前均經過顧問委員會的同行評議,詞條中均含有詞匯表、引言、參考文獻和豐富的交叉參考內容。主編為著名神經科學家、美國神經科學學會前主席LarryR.Squire。內容平易,本科生即可讀懂。深度和廣度獨一無二,足可滿足專家學者的需要。導讀版精選原書中的部分主題,按內容重新編排,更適合國內讀者購買和閱讀。
節律與同步-神經科學百科全書-14 相關資料
插圖:The alternation of light and dark is the most reliable timing cue on our planet, and therefore it is not surprising that the retina has evolved a precise timing mechanism that allows it to anticipate and then to adapt to the more than 1 million-fold change in light intensity during a 24 h period. The retina was the first extra-SCN oscillator to be discovered in mammals. Several studies have now demonstrated that many of the physiological, cellular, and molecular rhythms that are present within the retina are under the control of a circadian clock, or more likely a series of circadian clocks that are present within this tissue (Figure 1). For example, the disk shedding that occurs in the rod photoreceptors is under circadian control. Shedding persists in animals with SCN lesions or a transected optic nerve, indicating its independence from the central circadian pacemaker. Additional studies have reported that sensitivity to light-induced photoreceptor damage is modulated by the circadian clock via a cyclic adenosine monophosphate (cAMP)-dependent pathway. Other important retinal functions, such as visual sensitivity, are also under circadian control. Although results from these studies suggested that retinal physiology was regulated by a circadian clock, they were not sufficient to conclude that an independent circadian pacemaker was located within the retinal tissue. The definitive demonstration of the presence of an autonomous retinal clock in mammals was achieved a few years ago when it was shown that a circadian rhythm of melatonin release persisted in mammalian retinas maintained in culture. In light/ dark cycles, melatonin levels were high during the night and low during the day. In constant darkness, the circadian rhythm of melatonin release free-ran, exhibiting a period close to 24 h. The circadian rhythm of melatonin release in the retina can be entrained by light in vitro and is temperature compensated. Such results demonstrated that the retina can be considered a bona fide circadian pacemaker, since it satisfies the three fundamental properties (i.e., freerunning, entrainment, and temperature compensation) that describe a circadian rhythm.
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