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調強放療中計算機應用技術研究 版權信息
- ISBN：9787121476105
- 條形碼：9787121476105 ; 978-7-121-47610-5
- 裝幀：平塑勒
- 冊數：暫無
- 重量：暫無
- 所屬分類：>>
調強放療中計算機應用技術研究 本書特色
計算機應用技術 調強放療 劑量計算 放療計劃系統 調強規劃模型 放射生物學模型 自動勾畫 凸優化求解 劑量驗證
調強放療中計算機應用技術研究 內容簡介
本書從調強放療的步驟入手，概括介紹常用的放療設備、照射方式、放療目的、放療的生物學原理等；重點介紹調強放療中的計算機應用技術，涉及劑量計算模型、放療計劃系統中的可行性問題，以及線性和非線性規劃模型、放射生物學模型、帶有劑量體積約束的規劃模型、多目標規劃模型、照射角度選擇優化模型等。此外，本書對通量圖的生成和調制、基于機器跳數的平滑方法和雙向葉片運動通量圖平滑模型等進行研究；討論自動勾畫的意義、需求和定義等，介紹閾值分割算法、區域分割算法、分水嶺分割算法和馬爾可夫隨機場分割算法等常見的圖像分割算法，重點介紹一種加入區域信息的測地線活動輪廓模型、一種改進的V-Net 模型和一種基于等效生物劑量和硬件約束的一體化逆向計劃模型，并介紹凸優化求解和劑量驗證等。本書介紹的內容涉及面廣，有助于讀者了解調強放療中的計算機應用技術，適合作為高等學校醫學影像處理相關專業研究生和高年級本科生的教材，也適合相關科研人員和對調強放療技術感興趣的讀者閱讀。
調強放療中計算機應用技術研究 目錄
第1 章 引言······················································································1
1.1 研究背景及意義······································································1
1.1.1 癌癥的嚴重危害·····························································1
1.1.2 癌癥的治療方法·····························································3
1.1.3 放療對于癌癥治療的貢獻················································4
1.1.4 放療技術發展的巨大潛力················································5
1.2 放療技術的發展歷史································································8
1.2.1 初級放療時代································································8
1.2.2 常規放療時代································································9
1.2.3 精準放療時代································································9
1.2.4 小結·········································································.10
1.3 計算機應用技術對調強放療技術的支撐作用·······························.11
第2 章 放療中的硬件及放療計劃系統·················································.13
2.1 放療的分類·········································································.13
2.1.1 基本概念···································································.13
2.1.2 放療設備···································································.17
2.1.3 照射方式···································································.28
2.1.4 放療目的···································································.32
2.1.5 放療手段和技術··························································.33
2.1.6 劑量分割方式·····························································.37
2.2 放療的生物學原理································································.38
2.3 調強放療的步驟···································································.40
2.4 調強放療中的射線調制設備····················································.43
2.5 逆向計劃系統······································································.45
第3 章 調強放療中的規劃問題···························································.48
3.1 正向調強規劃和逆向調強規劃·················································.48
3.1.1 正向調強規劃·····························································.48
3.1.2 逆向調強規劃·····························································.49
3.2 調強放療中的數學優化問題····················································.49
3.3 劑量計算模型和相關描述·······················································.50
3.4 放療計劃系統中的可行性問題·················································.51
3.5 調強放療中的規劃模型··························································.51
3.5.1 線性和非線性規劃模型················································.51
3.5.2 放射生物學模型··························································.53
3.5.3 劑量體積約束模型·······················································.56
3.5.4 劑量體積約束優化問題················································.60
3.5.5 規范化距離信息排序···················································.63
3.5.6 混合整數規劃模型·······················································.68
3.5.7 多目標規劃模型··························································.69
3.5.8 照射角度選擇優化模型················································.72
第4 章 通量圖的平滑方法·································································.75
4.1 通量圖的生成和調制·····························································.75
4.2 通量圖的平滑······································································.78
4.3 圖像去噪原理······································································.79
4.4 基于機器跳數的平滑方法·······················································.83
4.4.1 基于圖像處理的平滑方法存在的問題······························.83
4.4.2 基于多葉準直器的靜態調強放療的劑量調制過程···············.84
4.4.3 無葉片碰撞約束的模型················································.87
4.4.4 后驅葉片同步約束模型················································.88
4.4.5 前驅葉片同步約束模型················································.90
4.4.6 前后葉片中心時長同步模型··········································.91
4.4.7 舌槽欠劑量效應的直接約束··········································.94
4.4.8 帶葉片碰撞約束的模型················································.95
4.5 雙向葉片運動通量圖平滑模型·················································.96
4.5.1 雙向葉片運動通量圖平滑模型介紹·································.96
4.5.2 實驗及結果分析······················································
1.1 研究背景及意義······································································1
1.1.1 癌癥的嚴重危害·····························································1
1.1.2 癌癥的治療方法·····························································3
1.1.3 放療對于癌癥治療的貢獻················································4
1.1.4 放療技術發展的巨大潛力················································5
1.2 放療技術的發展歷史································································8
1.2.1 初級放療時代································································8
1.2.2 常規放療時代································································9
1.2.3 精準放療時代································································9
1.2.4 小結·········································································.10
1.3 計算機應用技術對調強放療技術的支撐作用·······························.11
第2 章 放療中的硬件及放療計劃系統·················································.13
2.1 放療的分類·········································································.13
2.1.1 基本概念···································································.13
2.1.2 放療設備···································································.17
2.1.3 照射方式···································································.28
2.1.4 放療目的···································································.32
2.1.5 放療手段和技術··························································.33
2.1.6 劑量分割方式·····························································.37
2.2 放療的生物學原理································································.38
2.3 調強放療的步驟···································································.40
2.4 調強放療中的射線調制設備····················································.43
2.5 逆向計劃系統······································································.45
第3 章 調強放療中的規劃問題···························································.48
3.1 正向調強規劃和逆向調強規劃·················································.48
3.1.1 正向調強規劃·····························································.48
3.1.2 逆向調強規劃·····························································.49
3.2 調強放療中的數學優化問題····················································.49
3.3 劑量計算模型和相關描述·······················································.50
3.4 放療計劃系統中的可行性問題·················································.51
3.5 調強放療中的規劃模型··························································.51
3.5.1 線性和非線性規劃模型················································.51
3.5.2 放射生物學模型··························································.53
3.5.3 劑量體積約束模型·······················································.56
3.5.4 劑量體積約束優化問題················································.60
3.5.5 規范化距離信息排序···················································.63
3.5.6 混合整數規劃模型·······················································.68
3.5.7 多目標規劃模型··························································.69
3.5.8 照射角度選擇優化模型················································.72
第4 章 通量圖的平滑方法·································································.75
4.1 通量圖的生成和調制·····························································.75
4.2 通量圖的平滑······································································.78
4.3 圖像去噪原理······································································.79
4.4 基于機器跳數的平滑方法·······················································.83
4.4.1 基于圖像處理的平滑方法存在的問題······························.83
4.4.2 基于多葉準直器的靜態調強放療的劑量調制過程···············.84
4.4.3 無葉片碰撞約束的模型················································.87
4.4.4 后驅葉片同步約束模型················································.88
4.4.5 前驅葉片同步約束模型················································.90
4.4.6 前后葉片中心時長同步模型··········································.91
4.4.7 舌槽欠劑量效應的直接約束··········································.94
4.4.8 帶葉片碰撞約束的模型················································.95
4.5 雙向葉片運動通量圖平滑模型·················································.96
4.5.1 雙向葉片運動通量圖平滑模型介紹·································.96
4.5.2 實驗及結果分析······················································
展開全部
調強放療中計算機應用技術研究 作者簡介
蘭義華，南陽師范學院計算機與信息技術學院副教授，博士，博士后。2011年12月博士畢業于華中科技大學計算機應用技術專業，2017年11月從華中科技大學軟件工程博士后流動站出站。河南省重點學科計算機應用學科帶頭人，河南省教育廳學術技術帶頭人，南陽市學術技術帶頭人，南陽師范學院"臥龍學者”特聘研究員崗位入選者，計算機學會高級會員。
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