PART SECTION 1 DISORDERS OF THE RESPIRATORY SYSTEM Chapter 1 Approach to the Patient with Disease of the Respiratory System Chapter 2 Disturbances of Respiratory Function Chapter 3 Diagnostic Procedures in Respiratory Disease Chapter 4 Approach to the Patient with Critical Illness Chapter 5 Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia Chapter 6 Asthma Chapter 7 Chronic Obstructive Pulmonary Disease Chapter 8 Pneumonia Chapter 9 Bronchiectasis and Lung Abscess Chapter 10 Occupational and Environmental Lung Disease Chapter 11 Interstitial Lung Diseases Chapter 12 Neoplasms of the Lung Chapter 13 Disorders of the Pleura and Mediastinum Chapter 14 Deep Venous Thrombosis and Pulmonary Thromboembolism Chapter 15 Sleep Apnea Chapter 16 Disorders of Ventilation Chapter 17 Acute Respiratory Distress Syndrome Chapter 18 Mechanical Ventilatory Support Chapter 19 Lung Transplantation SECTION 2 DISORDERS OF THE CARDIOVASCULAR SYSTEM Chapter 1 Basic Biology of the Cardiovascular System Chapter 2 Epidemiology of Cardiovascular Disease Chapter 3 Approach to the Patient with Possible Cardiovascular Disease Chapter 4 Physical Examination of the Cardiovascular System Chapter 5 Electrocardiography Chapter 6 Nuclear Cardiology Chapter 7 Diagnostic Cardiac Catheterization and Coronary Angiography Chapter 8 Principles of Electrophysiology Chapter 9 The Bradyarrhythmias Chapter 10 The Tachyarrhythmias Chapter 11 Heart Failure and Cor Pulmonale Chapter 12 Cardiac Transplantation and Prolonged Assisted Circulation Chapter 13 Congenital Heart Disease in the Adult Chapter 14 Valvular Heart Disease Chapter 15 Cardiomyopathy and Myocarditis Chapter 16 Pericardial Disease Chapter 17 Tumors of and Trauma of the Heart Chapter 18 The Pathogenesis Prevention, and Treatment of Atherosclerosis Chapter 19 The Metabolic Syndrome Chapter 20 Ischemic Heart Disease Chapter 21 Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction Chapter 22 ST-Segment Elevation Myocardial Infarction Chapter 23 Percutaneous Coronary Interventions and Other Interventional Procedures Chapter 24 Hypertensive Vascular Disease Chapter 25 Diseases of the Aorta Chapter 26 Vascular Diseases of the Extremities Chapter 27 Pulmonary Hypertension Chapter 28 Cardiogenic Shock and Pulmonary Edema Chapter 29 Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death SECTION 3 DISORDERS OF THE GASTROINTESTINAL SYSTEM Chapter 1 Approach to the Patient with Gastrointestinal Diseases Chapter 2 Gastrointestinal Endoscopy Chapter 3 Diseases of the Esophagus Chapter 4 Peptic Ulcer Disease Chapter 5 Gastritis Chapter 6 Inflammatory Bowel Disease Chapter 7 Irritable Bowel Syndrome Chapter 8 Diverticular Disease and Common Anorectal Disorders Chapter 9 Mesenteric Vascular Insufficiency Chapter 10 Disorders of Absorption Chapter 11 Acute Intestinal Obstruction and Peritonitis Chapter 12 Approach to the Patient with Liver Disease Chapter 13 Evaluation of Liver Function Chapter 14 The Hyperbilirubinemias Chapter 15 Acute Viral Hepatitis Chapter 16 Toxic and Drug-Induced Hepatitis Chapter 17 Chronic Hepatitis Chapter 18 Alcoholic Liver Disease Chapter 19 Cirrhosis and Its Complications Chapter 20 Genetic, Metabolic, and Infiltrative Diseases Affecting the Liver Chapter 21 Approach to the Patient with Pancreatic Disease Chapter 22 Acute and Chronic Pancreatitis Chapter 23 Gastrointestinal Tract Cancer Chapter 24 Tumors of the Liver and Biliary Tree SECTION 4 DISORDERS OFTHE KIDNEYAND URINARYTRACT Chapter 1 Cellular and Molecular Biology of the Kidney Chapter 2 Adaption of the Kidney to Renal Injury Chapter 3 Acute Kidney Injury Chapter 4 Chronic Kidney Disease Chapter 5 Dialysis in the Treatment of Renal Failure Chapter 6 Transplantation in the Treatment of Renal Failure Chapter 7 Glomerular Diseases Chapter 8 Polycystic Kidney Disease and Other Inherited Tubular Disorders Chapter 9 Tubulointerstitial Diseases of the Kidney Chapter 10 Vascular Injury to the Kidney Chapter 11 Nephrolithiasis Chapter 12 Urinary Tract Infections, Pyelonephritis, and Prostatitis Chapter 13 Urinary Tract Obstruction PART SECTION 5 DISORDERS OF THE HEMATOPOIETIC SYSTEM Chapter 1 Iron Deficiency and Other Hypoproliferative Anemias Chapter 2 Disorders of Hemoglobin Chapter 3 Megaloblastic Anemias Chapter 4 Hemolytic Anemias and Anemia Due to Acute Blood Loss Chapter 5 Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes Chapter 6 Polycythemia Vera and Other Myeloproliferative Diseases Chapter 7 Acute and Chronic Myeloid Leukemia Chapter 8 Malignancies of Lymphoid Cells Chapter 9 Plasma Cell Disorders Chapter 10 Amyloidosis Chapter 11 Transfusion Biology and Therapy Chapter 12 Hematopoietic Cell Transplantation Chapter 13 Disorders of Platelets and Vessel Wall Chapter 14 Coagulation Disorders Chapter 15 Arterial and Venous Thrombosis Chapter 16 Antiplatelet, Anticoagulant, and Fibrinolytic Drugs SECTION 6 DISORDERS OF THE ENEOCRINOLOGY AND METABOLISM Chapter 1 Principles of Endocrinology Chapter 2 Disorders of the Anterior Pituitary and Hypothalamus Chapter 3 Disorders of the Neurohypophysis Chapter 4 Disorders of the Thyroid Gland Chapter 5 Disorders of the Adrenal Cortex Chapter 6 Pheochromocytoma Chapter 7 Diabetes Mellitus Chapter 8 Hypoglycemia Chapter 9 Disorders of the Testes and Male Reproductive System Chapter 10 The Female Reproductive System, Infertility, and Contraception Chapter 11 The Menopause Transition and Postmenopausal Hormone Therapy Chapter 12 Disorders of Sex Development Chapter 13 Neuroendocrine Neoplasm and Multiple Endocrine Neoplasia Chapter 14 Bone and Mineral Metabolism in Health and Disease Chapter 15 Disorders of the Parathyroid Gland and Calcium Homeostasis Chapter 16 Osteoporosis Chapter 17 Dyslipidemia Chapter 18 Hyperuricemia SECTION 7 DISORDERS OFTHE RHEUMATIC IMMUNE SYSTEM Chapter 1 Introduction to the Immune System Chapter 2 The Major Histocompatibility Complex Chapter 3 Primary Immune Deficiency Diseases Chapter 4 Allergies, Anaphylaxis, and Systemic Mastocytosis Chapter 5 Autoimmunity and Autoimmune Diseases Chapter 6 Systemic Lupus Erythematosus Chapter 7 Antiphospholipid Antibody Syndrome Chapter 8 Rheumatoid Arthritis Chapter 9 Acute Rheumatic Fever Chapter 10 Systemic Sclerosis (Scleroderma) and Related Disorders Chapter 11 Sj.gren's Syndrome Chapter 12 The Spondyloarthritides Chapter 13 The Vasculitis Syndromes Chapter 14 Beh.et's Syndrome Chapter 15 Relapsing Polychondritis Chapter 16 Sarcoidosis Chapter 17 Familial Mediterranean Fever Chapter 18 Approach to Articular and Musculoskeletal Disorders Chapter 19 Osteoarthritis Chapter 20 Gout Chapter 21 Infectious Arthritis Chapter 22 Fibromyalgia Chapter 23 Arthritis Associated with Systemic Disease, and OtherArthritides Chapter 24 Periarticular Disorders of the Extremities SECTION 8 DISORDERS OF THE NEUROLOGIC SYSTEM Chapter 1 Biology of Neurologic Diseases Chapter 2 Approach to the Patient with Neurologic Disease Chapter 3 Neuroimaging in Neurologic Disorders Chapter 4 Seizures and Epilepsy Chapter 5 Cerebrovascular Diseases Chapter 6 Dementia Chapter 7 Parkinson's Disease and Other Movement Disorders Chapter 8 Ataxic Disorders Chapter 9 Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases Chapter 10 Trigeminal Neuralgia, Bell's Palsy, and Other Cranial Nerve Disorders Chapter 11 Diseases of the Spinal Cord Chapter 12 Multiple Sclerosis and Other Demyelinating Diseases Chapter 13 Meningitis, Encephalitis, Brain Abscess, and Empyema Chapter 14 Chronic and Recurrent Meningitis Chapter 15 Prion Diseases Chapter 16 Peripheral Neuropathy Chapter 17 Guillain-Barr�� Syndrome and Other Immune-Mediated Neuropathies Chapter 18 Myasthenia Gravis and Other Diseases of the Neuromuscular Junction Chapter 19 Muscular Dystrophies and Other Muscle Diseases Chapter 20 Polymyositis, Dermatomyositis, and Inclusion Body Myositis